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#skincancer

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I had an ADHD event this morning. I used to explain these away or blame them on external causes or other people.

If I’d taken my meds when I woke, I would’ve been fine, but I didn’t. I tried to do too much before leaving for my appointment, jumped on the wrong tram, had to call an Uber, then got confused about the meeting point. Rang my skin guy & was able to rejigger appointment, which gave me time for a decaf & a decompress.

My oldest has always been more philosophical than me on these things, better at accepting that it is what it is and then adjusting. I used to be good at doing that when others stuffed up (but maybe less patient with my oldest) but would get very upset about my own occasional dramas, maybe because underneath my externalisation of responsibility, I knew it was me.

But this morning I just accepted I’d stuffed up, did what I had to do & accepted that I might have to rebook the appointment. Fortunately they were able to juggle. The worst part is causing other people inconvenience. I’m acutely aware of that, maybe because of RSD? (Rejection Sensitive Dysphoria)

Uber driver was a lovely Manchurian who has his skin check booked. 😊Currently waiting for anaesthetic to take effect.

#ADHD #actuallyautistic @actuallyautistic #SkinCancer

Just got a call from my skin guy. The spot he removed last week was a basal cell carcinoma, So I’m going back in tomorrow to have a bit more skin removed. I’ve had a few spots removed, but this & the last one were the only cancers. This is why I have 6 monthly skin checks, to catch them early. Get your skin checked! #SkinCancer

#Marijuana Extract Can Kill #Melanoma Cells, New Study Reveals Possible Treatment For #SkinCancer

Story by Nina Zdinjak

February 8, 2024

"A new study indicates #cannabis has the potential to treat melanoma, a skin cancer beginning in the melanocyte cells, which make the pigment that gives skin its color.

"Melanoma typically results from over-exposure to the sun. While skin cancer is one of the most common cancers in the United States, melanoma accounts for only about 1%, yet causes a large majority of skin cancer deaths, according to the American Cancer Society.

"New research published in a peer-reviewed Cell Journal conducted by scientists from Charles Darwin University (CDU) and RMIT University offers hope for the creation of a natural treatment for melanoma.

"The study, part of a Ph.D. project by RMIT's Dr. Ava Bachari, showed that a specific cannabis extract (#PHEX66) from the #CannabisSativa plant binds to receptor sites on particular melanoma cells, controlling its growth at two key phases and increasing the amount of damage to these cells.

"Dr. Nazim Nassar, the study co-author and CDU pharmaceutical lecturer said this damage practically tricks cells into killing itself, writes Mirage News. This inhibitory effect arises from interactions with #CB1 and #CB2 receptors, the paper reads.

"'The damage to the melanoma cell prevents it from dividing into new cells, and instead begins a programmed cell death, also known as #apoptosis,' Dr. Nassar said. 'This is a growing area of important research because we need to understand cannabis extracts as much as possible, especially their potential to function as anticancer agents. If we know how they react to cancer cells, particularly in the cause of cell death, we can refine treatment techniques to be more specific, responsive and effective'.

"According to Nassar, who specializes in cancer cell biology, pharmacology and drug delivery systems, the next step should be to create a targeted delivery system for the melanoma cells in preparation for pre-clinical trials.

"'Clinical uses of cannabis extracts include treatment for anxiety, cancer-related symptoms, epilepsy, and chronic pain. Intensive research into its potential for killing melanoma cells is only the start as we investigate how this knowledge can be applied to treating different types of cancers,' Nassar said.

"Professor Nitin Mantir, lead author and RMIT biotechnologist, said there needs to be a thorough follow-up to assess the long-term efficiency and safety of the PHEC-66 extract.

"'The subsequent stage involves animal studies or pre-clinical trials to validate and further explore the efficacy of cannabinoid PHEC-66 in treating melanoma and other cancers,' Mantri said.

"Both authors stressed the need for support and sponsorship to eventually qualify PHEC-66 as a registered medicine."

msn.com/en-us/health/other/mar

www.msn.comMSN

US Teen Wins Top Prize For Inventing a Soap to Fight Skin Cancer
A 14-year-old US scientist has developed a soap that could help the body's immune system 'wash away' skin cancer.
The soap has won him the top prize in the Young Scientist's Challenge, an annual competition aimed to encourage children and adolescents to innovate solutions to everyday problems.
sciencealert.com/us-teen-wins- #soap #SkinCancer #invention #teen #imidazoquinoline

ScienceAlert · US Teen Wins Top Prize For Inventing a Soap to Fight Skin CancerA 14-year-old US scientist has developed a soap that could help the body's immune system 'wash away' skin cancer.

The #mutation that removed the SLC24A5 and SLC45A2 genes results in depigmentation of the skin.

It was claimed that this allows people to produce #vitaminD even when it is cloudy. However, it is now known that one only needs to be exposed to the outdoor for an hour even when it is cloudy to produce enough vitamin D. Prehistoric people were farmers or hunter gatherers who had to stay outside. How could they not get #skincancer #skincolor

ncbi.nlm.nih.gov/pmc/articles/.

raoptics.com/blogs/news/can-i-.

PubMed Central (PMC)Proposed Genetic Classification for the Skin Types: Helmy’s Skin Types Classification