(1/2) Saw something new to me while using #Synaptic. I downloaded the pack of Rogue-like retro games from the #Debian repositories.

The packages downloaded, but then hung up on the actual installs. I clicked the link to expand the details and I could see in the dialogue that there was a "Hearse" prompt and it was waiting for me to input an email address. Had I not expanded the details, I would have never seen this and just assumed there was some kind of error and aborted the install...

Conflicting results have been obtained re changes in synaptic strength in the #CerebralCortex during the #Sleep-WakeCycle. This computational study provides a comprehensive understanding & unified framework about #synaptic dynamics during #sleep & wake states @PLOSBiology https://plos.io/4kHeNwM

Liprin-α & RIM form presynaptic liquid phase-separated condensates #LLPS. This Primer explores a @PLOSBiology study of how these assemblies shape #synaptic fidelity and what their disruption might mean in #neurodevelopmental disease. Paper: https://plos.io/3Tj5CX7 Primer: https://plos.io/3HTacJ9

How do scaffolding proteins regulate the assembly of #presynaptic #ActiveZones? This study solves the structure of the liprin-α2/RIM1 complex & shows that it is essential for #synaptic transmission and LLPS-dependent coupling of Ca2+ channels & synaptic vesicles @PLOSBiology https://plos.io/3Tj5CX7

Ufficio Zero Linux Lorena - Guida alla configurazione iniziale

https://youtu.be/9xMbbbzlRc4

Come da vostra richiesta, ecco un video dove parliamo meglio di questa distribuzione MADE in ITALY basata su PCLinuxOS.
Buona visione

@ufficiozero @ufficiozero@pixelfed.uno @ufficiozerolinuxos #windows #opensourceitalia #ufficiozerolinux #gnulinux #pclinuxos #rpm #synaptic

A computational modeling approach reveals how local changes in potassium concentration regulate dendritic integration of #synaptic inputs, revealing that 'potassium hotspots’ act as a gain control mechanism #PLOSBiology https://plos.io/49rlAWo

He publicado nuevo vídeo en mi canal de Youtube: 3 trucos para SYNAPTIC: Limpiar config residual, listar paquetes instalados, activar filtro rápido #Synaptic #Debian https://www.youtube.com/watch?v=c1WAAT2nq_c

Great #review on normative #synaptic #plasticity models from Colin Bredenberg and Cristina Savin:

https://arxiv.org/abs/2308.04988

Postdoctoral Position in Neuroepigenetics

The University of Michigan Medical School

#Postdoc position in the joint labs by Sutton and Iwase at the University of Michigan, combining expertise in #synaptic #plasticity and #epigenetics.

See the full job description on jobRxiv: https://jobrxiv.org/job/the-university-of-michigan-medical-school-27778-postdoctoral-posi...
https://jobrxiv.org/job/the-university-of-michigan-medical-school-27778-postdoctoral-position-in-neuroepigenetics/?feed_id=54449

Postdoctoral Position in Neuroepigenetics

The University of Michigan Medical School

#Postdoc position in the joint labs by Sutton and Iwase at the University of Michigan, combining expertise in #synaptic #plasticity and #epigenetics.

See the full job description on jobRxiv: https://jobrxiv.org/job/the-university-of-michigan-medical-school-27778-postdoctoral-posi...
https://jobrxiv.org/job/the-university-of-michigan-medical-school-27778-postdoctoral-position-in-neuroepigenetics/?feed_id=54426

A synapse-by-synapse map of a brain

Complete synaptic-resolution connectomes have until now only been mapped for three organisms with up to several hundred brain neurons. Winding et al. describe a three-dimensional electron microscopy–based reconstruction of the larval fruit fly brain. The brain of the Drosophila larva has an order of magnitude more neurons, an even greater scale more synapses, and a complex brain organization.

#Neuroscience #Brain #Connectome #Connectomics #Synapses #Synaptic #Drosophila

https://www.science.org/doi/10.1126/science.add9330

Do you use a graphical software manager?

Boost for more range

#behavioural time-scale #synaptic #plasticity was discovered by Bittner and Magee a few years ago: https://www.science.org/doi/full/10.1126/science.aan3846

It was mysterious - how could the time-window for plasticity be so large?

This new paper from the Losonczy lab suggests that it's due to intracellular calcium release from the ER:

https://www.science.org/doi/abs/10.1126/science.abm1670